AlkaneBase

ABA55763 ABA55774 ABA55783

ABA55787 AFC90115 AFC90116

AFC90117 AFQ37251 AFQ37252

KP221807 AFQ37256 AFQ37258

AFQ37259 AGJ00850 AGJ00851

BAE47476 BAE47487 CAH56107

CAJ01370 CAJ01371

References

[1] Amann, R.I., et al. Phylogenetic identification and in situ detection of individual microbial cells without cultivation, Microbiol. Rev. 59, 143--169, 1995.

[2] Schmidt, T.M., et al. Analysis of a marine picoplankton community by 16S rRNA gene cloning and sequencing, J. Bacteriol. 173, 4371--4378, 1991.

[3] Marco, D. Metagenomics: Theory, Methods and Applications. Caister Academic Press, U.K., 2010.

[4] Marco, D. Metagenomics: Current Innovations and Future Trends. Caister Academic Press, U.K., 2011.

[5] Voget, S., et al. Prospecting for novel biocatalysts in a soil metagenome, Appl. Environ. Microbiol. 69, 6235--6242, 2003.

[6] Henne, A., et al. Construction of environmental DNA libraries in Escherichia coli and screening for the presence of genes conferring utilization of 4- hydroxybutyrate, Appl. Environ. Microbiol. 65, 390--397, 1999.

[7] Entcheva, P., et al. Direct cloning from enrichment cultures, a reliable strategy for isolation of complete operons and genes from microbial consortia, Appl. Environ. Microbiol. 67, 89--99, 2001.

[8] Benson, S., et al. Fractionation of inducible alkane hydroxylase activity in Pseudomonas putida and characterization of hydroxylase-negative plasmid mutations, J. Bacteriol. 132, 614--621, 1977.

[9] Peterson, J. A, et al. Enzymatic omega-oxidation of electon carriers in fatty acid and hydrocarbon hydroxylation, J. Biol. Chem. 241, 516--5164, 1966.

[10] Benson, S., et al. Regulation of membrane peptides by the Pseudomonas plasmid alk regulon, J. Bacteriol. 140, 754--762, 1979.

[11] McKenna, E. J., & Coon, M. J. Enzymatic omega-oxidation. IV. Purification and properties of the omega-hydroxylase of Pseudomonas oleovorans, J. Biol. Chem. 245, 3882--3889, 1970.

[12] Ruettinger, R. T., et al. Identification of the omega-hydroxylase of Pseudomonas oleovorans as a nonheme iron protein requiring phospholipid for catalytic activity, Biochem. Biophys. Res. Commun. 57, 1011--1017, 1974.

[13] Lode, E. T. & Coon, M. J. Enzymatic omega-oxidation. V. Forms of Pseudomonas oleovorans rubredoxin containing one or two iron atoms: structure and function in omega-hydroxylation, J. Bwl. Chem. 246, 791--802, 1971.

[14] van Beilen, J.B. & Funhoff, E.G Alkane hydroxylases involved in microbial alkane degradation, Appl. Microbiol. Biotechnol. 74, 13--21, 2007.

[15] van Beilen, J.B., & Funhoff, E.G. Expanding the alkane oxygenase toolbox: new enzymes and applications, Curr. Opin. Biotechnol. 16, 308--314, 2005.

[16] Li, Z., et al. Preparation of (R)- and (S)-N-protected 3-hydroxypyrrolidines by hydroxylation with Sphingomonas sp. HXN-200, a highly active, regio and stereo selective, and easy-to-handle biocatalyst, J. Org. Chem. 66, 842--8430, 2001.

[17] Witholt, B., et al. Bioconversions of aliphatic compounds by Pseudomonas oleovorans in multiphase biorectors: background and economic potential, Trends Biotechnol. 8, 46--52, 1990.

[18] Whyte, L.G., et al. Gene cloning and characterization of multiple alkane hydroxylase systems in Rhodococcus strains Q15 and NRRL B-16531, Appl. Environ. Microbiol. 68, 5933--5942, 2002.

[19] Zhang, Y. I-TASSER server for protein 3D structure prediction, BMC Bioinformatics, 9, 40--50, 2008.

[20] Roy. A., et al. Y. I-TASSER: a unified platform for automated protein structure and function prediction, Nature Protocols, 5, 725--738, 2010.

[21] Roy. A., et al. COFACTOR: An accurate comparative algorithm for structure-based protein function annotation, Nucleic Acids Research, 40, W471--W477, 2012.